Multiple acantholytic dyskeratotic acanthomas in a liver-transplant recipient

Area of Science:

• Dermatopathology
• Transplant Surgery

Background:

• Acantholytic dyskeratotic acanthoma is a rare epidermal neoplasm.
• Pathological hallmarks include acantholysis and dyskeratosis.
• Previous reports are scarce, with one case in a heart-transplant recipient.

Observation:

• A novel case of acantholytic dyskeratotic acanthoma is presented.
• The lesion developed in a patient who had undergone a liver transplant.
• This highlights a potential association in immunosuppressed individuals.

Findings:

• The case confirms the characteristic pathological features of acantholysis and dyskeratosis.
• It expands the clinical spectrum of this rare condition in transplant recipients.
• Review of existing literature provides context for this new observation.

Implications:

• This case contributes to understanding rare skin conditions post-transplantation.
• It underscores the importance of monitoring for unusual dermatological findings in immunosuppressed patients.
• Further research may elucidate the specific factors contributing to its development in transplant recipients.