Related Experiment Video
Updated: Jan 25, 2026

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
Published on: August 28, 2020
Medullary Hot-Cross Bun Sign in Multiple System Atrophy-Cerebellar
Rajendra Singh Jain1, Sunil Kumar1, Shankar Tejwani2
1Department of Neurology, Sawai Man Singh Medical College, Jaipur, Rajasthan, India.
Abstract:
Multiple-system atrophy (MSA) is a progressive neurodegenerative disorder. It is characterized by dysfunction of multiple systems including autonomic, extrapyramidal, pyramidal and cerebellar. Pontine hot-cross bun (HCB) sign in MSA is a well-documented and highly specific entity. To the best of our knowledge, medullary hot-cross bun (HCB) sign has never been described in literature. Herein, we report a case of MSA-C with medullary HCB sign. Detection of medullary HCB sign might be a surrogate marker in the diagnosis of MSA-C, particularly in the absence of classical pontine HCB sign; however, further research will help to validate this sign.
Related Concept Videos
Signs of Puberty
Introduction to the Sign Test
Sign Convention
The normal force acts perpendicular to the beam's cross-section and can...
Cross-Sectional Research
Sign Test for Nominal Data
For example, consider a...
Introduction to Vital Signs
Vital signs help healthcare professionals assess an individual's well-being and detect any functional changes...

