Related Experiment Video
Updated: Jan 25, 2026

High-throughput Flow Cytometry Cell-based Assay to Detect Antibodies to N-Methyl-D-aspartate Receptor or Dopamine-2 Receptor in Human Serum
Published on: November 23, 2013
Preparation of functionalized double ratio fluorescent imprinted sensors for visual determination and recognition of
Yeqing Xu1, Jixiang Wang1, Yang Lu2
1Institute of Green Chemistry and Chemical Technology, School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, 212013, PR China.
Abstract:
Ratiometric fluorescent sensors have shown great prospect in chemical monitoring and recognition due to its high intuitiveness, accurateness, and visualization. In this work, the ratiometric fluorescent sensors, which includes a blue fluorescent Carbon quantum dots (CQDs) as internal standard material, and a red fluorescent boric acid-modified CdTe QDs as response signal. Then we choose dopamine (DA) as template, 3-phenylboronic acid (APBA) for functional monomers, tetraethyl orthosilicate (TEOS) for cross-linker to synthesize double ratio molecularly imprinted polymers (DR-MIPs) that can identify dopamine selectively and sensitively. The DR-MIPs has better capability of selective recognition, obvious anti-ion interference, rapid detection and good visualization. Furthermore, the unique DR-MIPs was proved as efficient visual sensors for determination of DA in human serum rapidly and efficiently. The DR-MIPs still displayed well accuracy, and the potential prospects of this smart sensor is clearly demonstrated in the context of modern clinical medicine.
Related Concept Videos
Imprinting
Genomic Imprinting and Inheritance
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
Serum Studies: Renal Function Tests
Fixing Double-strand Breaks
Odds Ratio
Poisson's Ratio

