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Updated: Jan 25, 2026

Wheel Running and Environmental Complexity as a Therapeutic Intervention in an Animal Model of FASD
Published on: February 2, 2017
[Environmental intervention in respiratory disease]
Ledit R F Ardusso1, Hugo E Neffen2, Enrique Fernández-Caldas3
1Servicio de Alergia e Inmunología, Hospital Provincial del Centenario, Rosario, Santa Fe, Argentina.
Abstract:
In recent years there has been a significant increase in the prevalence of allergic diseases despite advances in the understanding of the pathogenesis, the dissemination of guidelines for its management and the emergence of new drugs. The reasons for this increase are not fully established, but it is suggested that multiple environmental factors may be involved. Inhaled air contains numerous harmful agents in addition to environmental allergens. The main immediate respiratory clinical expression after inhaling this contaminated air is asthma and rhinitis. The activity of human beings has altered the outdoor environment by the emission of multiple pollutants and has produced an increasing climate change. It also has a notable impact on the development of respiratory pathology and the modification of air quality. The bibliography on the subject of environmental control is very broad and sometimes difficult to interpret. In order to be able to make precise, valid and simple indications for patients to accomplish with, four scientific societies of the Argentine Republic that deal with this type of diseases, have elaborated a document that contains information of easy access to all medical personal involved in the treatment of patients with asthma and / or rhinitis, that provides practical measures for the patients and the different public health systems about unmet needs in this complex issue.
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