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Updated: Jan 25, 2026

Site-Directed φC31-Mediated Integration and Cassette Exchange in Anopheles Vectors of Malaria
Published on: February 2, 2021
Proteome data of female Anopheles stephensi antennae
Ajeet Kumar Mohanty1, Gourav Dey2, Manish Kumar3
1ICMR - National Institute of Malaria Research, Field Unit, Campal, Panaji, Goa 403001, India.
Abstract:
Antennae of female Anopheles stephensi mosquitoes were dissected and lysed with 1% SDS. Proteins were extracted using ultra sonication and analyzed on high resolution mass spectrometer. Proteomic data was analyzed using two search algorithms SEQUEST and Mascot, resulting in the identification of 22,729 peptides corresponding to 3262 proteins. These proteins were characterized using different bioinformatics tools. VectorBase resource was used to assign Gene Ontology (GO) terms. Using Biomart tool ortholog information was fetched from the VectorBase database. Raw mass spectrometric data was deposited in ProteomeXchange Consortium via PRIDE partner repository in the public dataset PXD001128. Proteins involved in insecticide resistance and odorant binding were the most abundant in the antennae. The proteins identified in this study could be targeted for developing novel vector control strategy.
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