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Updated: Jan 25, 2026

Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
Published on: May 16, 2014
An insight into chiral monolithic stationary phases for enantioselective high-performance liquid chromatography
Ali Fouad1,2, Diana Ibrahim1, Frady G Adly1
1Chirality Program, School of Science, Faculty of Science and Technology, University of Canberra, ACT, Australia.
Abstract:
In this review, three main classes of chiral monolithic stationary phases, namely silica-, organic polymer-, and hybrid-based monolithic stationary phases, are covered. Their preparations, applications, and advantages compared with the conventional-packed and open-tubular capillary columns are discussed. A detailed description of the different types and techniques used for the introduction of chiral selectors into the monolithic matrices such as immobilization, functionalization, coating, encapsulation, and bonding. Special emphasis is given to the recent developments of chiral selectors in HPLC monolithic stationary phases during the past 18 years.
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