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Updated: Jan 25, 2026

Interlinked Macroporous 3D Scaffolds from Microgel Rods
Published on: June 16, 2022
Phosphinate-containing rhodol and fluorescein scaffolds for the development of bioprobes
Yuan Fang1, Gillian N Good2, Xinqi Zhou1
1Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588, USA. cstains2@unl.edu.
Abstract:
A series of phosphinate-containing rhodol and fluorescein dyes are disclosed. These new fluorophores increase the color palette of phosphinate-based xanthenes in the far-red spectral region. The new chemical functionality of these scaffolds is leveraged to produce a sensitive, no-wash imaging probe for cellular esterase activity. The reported phosphinate-containing dyes provide platforms for the further development of imaging probes and self-reporting delivery vehicles.
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