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Published on: September 26, 2018
A modest protective association between pet ownership and cardiovascular diseases: A systematic review and
Tzu-Lin Yeh1,2, Wei-Te Lei3,4, Shu-Jung Liu5
1Department of Family Medicine, Hsinchu MacKay Memorial Hospital, Hsinchu City, Taiwan.
Insights
Pet ownership does not impact overall cardiovascular mortality or disease risk. However, it is linked to reduced cardiovascular mortality in the general population and lower cardiovascular disease risk in those with existing conditions.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Cardiovascular diseases (CVD) remain a leading cause of mortality globally.
- The potential impact of lifestyle factors, such as pet ownership, on cardiovascular health is an area of ongoing research.
- Understanding these associations can inform public health strategies and individual health choices.
Purpose of the Study:
- To systematically investigate the relationship between pet ownership and cardiovascular (CV) outcomes, including all-cause mortality, CV mortality, and the risk of specific cardiovascular diseases.
- To synthesize evidence from existing studies to provide a comprehensive overview of the current research landscape.
Main Methods:
- A systematic review and meta-analysis of studies identified through comprehensive searches of major biomedical databases (PubMed, EMBASE, CINAHL, Cochrane).
- Inclusion criteria focused on publications examining the association between pet ownership and cardiovascular mortality and morbidity.
- Study quality was assessed using the Newcastle-Ottawa Scale.
Main Results:
- The review included 12 studies with nearly 500,000 participants, followed for an average of 8.7 years.
- Overall, pet ownership showed no significant association with adjusted all-cause mortality, CV mortality, or the risk of cardiovascular disease, myocardial infarction, or stroke.
- Subgroup analyses revealed a significant association between pet ownership and lower adjusted CV mortality in the general population and a reduced CVD risk in patients with established CVD.
Conclusions:
- Pet ownership is not generally associated with improved cardiovascular mortality or reduced risk of major cardiovascular events across the population.
- However, a potential benefit exists for reduced cardiovascular mortality in the general population and decreased cardiovascular disease risk among individuals with pre-existing cardiovascular conditions.
- Further research may be warranted to elucidate the mechanisms behind these specific associations.
Purpose:
Investigate the relationship between pet ownership and cardiovascular (CV) outcomes.
Methods:
We searched the PubMed, Ovid EMBASE, Cumulative Index to Nursing and Allied Health Literature, Cochrane Database of Systematic Reviews, and Cochrane Central Register of Controlled Trials databases up to August 2018. Eligible publications examining the association between pet ownership and all-cause and CV mortality (primary outcomes) and risks of cardiovascular disease (CVD), myocardial infarction (MI), and stroke (secondary outcomes) were included. We used the Newcastle-Ottawa Scale to assess the quality of the articles.
Results:
We included 12 studies, involving 488,986 participants (52.3% female, mean age 56.1 years), in our systematic review. The mean follow-up duration was 8.7 ± 6.3 years. Pet ownership had no association with adjusted all-cause mortality (odds ratio, OR = 1.01, 95% confidence interval, CI [0.94, 1.08], I2 = 76%), adjusted CV mortality (OR = 0.87, 95% CI [0.75, 1.00], I2 = 72%), or risk of cardiovascular disease (CVD) (OR = 0.87, 95% CI [0.72, 1.05], I2 = 73%), myocardial infarction (MI) (OR = 0.99, 95% CI [0.97, 1.01], I2 = 0%), or stroke (OR = 0.99, 95% CI [0.98, 1.01], I2 = 0%). However, subgroup analysis showed that pet ownership was associated with a lower adjusted CV mortality in the general population (OR = 0.93, 95% CI [0.86, 0.99], I2 = 27%) than in CVD patients. In patients with established CVD, pet ownership was associated with a lower adjusted CVD risk (OR = 0.71, 95% CI [0.60, 0.84], I2 = 0%).
Conclusion:
Pet ownership is not associated with adjusted all-cause or CV mortality, or risk of CVD, MI, or stroke, but it is associated with a lower adjusted CV mortality in the general population and a lower CVD risk in patients with established CVD.
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