Related Experiment Video
Updated: Jan 25, 2026

Measuring Blood Pressure in Mice using Volume Pressure Recording, a Tail-cuff Method
Published on: May 15, 2009
Unintended consequences of the new ACC/AHA blood pressure treatment guidelines
1University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA. schrysant@yahoo.com.
Insights
Recent hypertension guidelines recommend strict blood pressure control, potentially impacting patients significantly. This review examines the evolution of blood pressure treatment guidelines and their implications.
Area of Science:
- Cardiology
- Nephrology
- Public Health
Background:
- Hypertension is a critical risk factor for cardiovascular disease, heart failure, chronic kidney disease, and stroke.
- Blood pressure (BP) treatment guidelines have evolved, shifting towards stricter control, notably influenced by the SPRINT trial.
- The latest American College of Cardiology/American Heart Association (ACC/AHA) guidelines advocate for systolic BP below 130 mmHg and diastolic BP below 80 mmHg for all individuals.
Purpose of the Study:
- To review the current status of systolic blood pressure (SBP) control in light of recent treatment guidelines.
- To analyze the evolution of BP treatment guidelines and their potential social and economic consequences.
- To synthesize findings from a literature search on BP control and treatment guidelines from 2014-2018.
Main Methods:
- Conducted a MEDLINE search of English-language literature published between 2014 and 2018.
- Utilized keywords including 'hypertension', 'blood pressure control', 'intensive blood pressure control', 'blood pressure treatment guidelines', and 'benefits and risks of intensive blood pressure control'.
- Retrieved 26 relevant papers for review, supplemented with collateral literature predating 2014.
Main Results:
- Recent guidelines, such as those from the ACC/AHA, have redefined hypertension classification, moving from 'prehypertension' to 'stage 1 hypertension'.
- The shift towards stricter BP control recommendations may have substantial social and economic implications for patient populations.
- The review synthesizes current literature on the benefits and risks associated with intensive blood pressure control strategies.
Conclusions:
- The evolving landscape of hypertension management necessitates a thorough understanding of current guidelines and their patient impact.
- Further discussion is warranted regarding the benefits and risks of intensive blood pressure control in diverse patient groups.
- The review highlights the dynamic nature of hypertension treatment recommendations and the need for ongoing evaluation.
Abstract:
Hypertension is a major risk factor for cardiovascular disease, heart failure, chronic kidney disease and stroke. Therefore, its early detection and treatment are very important according to blood pressure (BP) treatment guidelines issued by the various scientific societies. Over the years, BP treatment guidelines have changed from strict control of BP to more relaxed control, and lately to a strict BP control influenced by the results of the SPRINT trial. The recently published BP treatment guidelines by the American College of Cardiology/American Heart Association (ACC/AHA) recommend a systolic BP (SBP) and diastolic BP reduction to less than 130 mmHg and less than 80 mmHg, respectively, for all ages, and have also changed the classification of hypertension by changing the term "prehypertension" of the JNC 7 (7th Joint National Committee) guidelines to "stage 1 hypertension". These changes could have significant social and economic consequences for the patients. In order to get a better perspective of the current status of SBP control, we conducted a MEDLINE search of the English language literature from 2014 to 2018 in connection with recent (2014-2018) BP treatment guidelines, using the terms 'hypertension', 'blood pressure control', 'intensive blood pressure control', 'blood pressure treatment guidelines', and 'benefits and risks of intensive blood pressure control', and 26 pertinent papers were retrieved. These papers together with collateral literature, which goes beyond the year 2014, will be discussed in this review.
Related Concept Videos
Pre-Procedural Guidelines for Assessing Blood Pressure
Blood Pressure
Blood Pressure
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the...
Measurement of Blood Pressure
Factors affecting Blood pressure
Physiological Factors:
Alterations in Blood Pressure
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...

