Regional localization of carbonic anhydrase genes CA1 and CA3 on human chromosome 8

The human carbonic anhydrase isozymes represent a family of homologous proteins which are important in respiratory function, fluid secretion, and maintenance of cellular acid-base homeostasis. Using somatic cell genetic techniques we have mapped two of the CA genes (CA1 and CA3) to human chromosome 8. In situ hybridization data demonstrates that both CA1 and CA3 map to the same region (q13-q22) of chromosome 8.