Related Experiment Video
Updated: Jan 25, 2026

Isolation and Quantification of Botulinum Neurotoxin From Complex Matrices Using the BoTest Matrix Assays
Published on: March 3, 2014
Clostridium botulinum Spores in Corn Syrup and Other Syrups
Timothy Lilly1, E Jeffery Rhodehamel1, Donald A Kautter1
1Division of Microbiology, Food and Drug Administration, Washington, DC 20204.
Abstract:
A total of 738 bottles of corn syrup and other products containing corn syrup (e.g., pancake, maple, waffle, and table syrups) was examined by a membrane filtration procedure for the presence of Clostridium botulinum spores. One each of 354 light and 271 dark corn syrups was presumptively positive for C. botulinum type A spores, but subsequent testing of the entire contents of both bottles proved negative. All other 113 syrups were negative. Results showed that corn syrup and other syrups currently on the market are not food sources of C. botulinum spores for infants.
Insights
Clostridium botulinum spores were not detected in corn syrup products. This study indicates that corn syrup and similar syrups are not a source of these spores for infants.
Area of Science:
- Food Microbiology
- Microbial Spoilage
- Food Safety
Background:
- Clostridium botulinum spores are a concern in food products, particularly for infants.
- Corn syrup is a common ingredient in various food products, including syrups.
Purpose of the Study:
- To determine the presence of Clostridium botulinum spores in commercially available corn syrup and related products.
- To assess the risk of these products as a source of C. botulinum for infant botulism.
Main Methods:
- A total of 738 bottles of corn syrup and other syrups were analyzed.
- Membrane filtration was used to detect the presence of Clostridium botulinum spores.
Main Results:
- Initial presumptive positives for C. botulinum type A spores in two corn syrup samples were not confirmed upon further testing.
- All 738 analyzed syrup products tested negative for C. botulinum spores.
Conclusions:
- Corn syrup and other syrups currently on the market do not appear to be a food source of Clostridium botulinum spores.
- These findings suggest a low risk of infant botulism associated with the consumption of these syrup products.
Related Concept Videos
Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin
The binding of dantrolene to the RYR1...
Formation of Species
Seedless Vascular Plants
Pollination and Flower Structure
The Angiosperm Life Cycle
C4 Pathway and CAM
C4 Pathway
The C4 pathway is used by plants such as...

