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Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

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Perspectives in Implementing Radiogenomics to Radiotherapy.

William Tyler Tran¹, Carol Gillies²

¹Odette Cancer Centre, Sunnybrook Health Sciences Centre.

Journal of Medical Imaging and Radiation Sciences

|May 5, 2019

Summary

This summary is machine-generated.

Radiogenomics explores genetic factors influencing radiation response, offering potential advancements in radiation oncology. Further research is needed to translate these genomic findings into clinical practice for personalized cancer treatment.

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Area of Science:

Genomics and Radiation Oncology

Background:

Genomics studies all nucleotide sequences within an organism's chromosomes.
Radiogenomics investigates the genetic basis of cellular responses to radiation and its clinical applications.

Purpose of the Study:

To introduce radiogenomics technology.
To discuss the potential impact of radiogenomics on radiotherapy practices.

Main Methods:

Literature search on PubMed using keywords: genomics, genes, pharmacogenomics, radiogenomics, dose painting, and dose sculpting.

Main Results:

Radiogenomics research shows significant promise for future radiation oncology.
Current findings require further translational research, rigorous testing, and validation.

Conclusions:

Radiogenomics offers a theoretical basis for understanding radiobiological response.
Future applications may identify genes for tissue-specific radiation resistance and tolerance, impacting radiotherapy.