Related Experiment Video
Updated: Jan 25, 2026

Isolating Malignant and Non-Malignant B Cells from lck:eGFP Zebrafish
Published on: February 22, 2019
The Emerging Role of Adiponectin in Female Malignancies
Luca Gelsomino1, Giuseppina Daniela Naimo2, Stefania Catalano3
1Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende (CS), Italy. lugelso@gmail.com.
Abstract:
Obesity, characterized by excess body weight, is now accepted as a hazardous health condition and an oncogenic factor. In different epidemiological studies obesity has been described as a risk factor in several malignancies. Some biological mechanisms that orchestrate obesity-cancer interaction have been discovered, although others are still not completely understood. The unbalanced secretion of biomolecules, called "adipokines", released by adipocytes strongly influences obesity-related cancer development. Among these adipokines, adiponectin exerts a critical role. Physiologically adiponectin governs glucose levels and lipid metabolism and is fundamental in the reproductive system. Low adiponectin circulating levels have been found in obese patients, in which its protective effects were lost. In this review, we summarize the epidemiological, in vivo and in vitro data in order to highlight how adiponectin may affect obesity-associated female cancers.
Related Concept Videos
Emerging Adulthood
Infertility in Females
Endometriosis, a condition characterized by abnormal growth of...
External Female Genitals
Disorders of the Female Reproductive System
Introduction Cardiac Emergencies
Applications of GIS: Disaster Management and Emergency Response

