The effect of alfentanil on experimental myocardial infarction size: a comparison with fentanyl and halothane

We compared the action of alfentanil on experimental myocardial infarction size with two widely used anesthetic drugs: fentanyl and halothane. Myocardial infarction size, measured by histological techniques, was identical for the three drugs investigated. Our results demonstrate that the action of alfentanil on factors governing myocardial oxygen supply and demand in the rat with coronary artery ligation is no different from the action of fentanyl or halothane.