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Updated: Jan 25, 2026

Measurements of Physiological Stress Responses in C. Elegans
Published on: May 21, 2020
Exploring Cellular Stress Response and Chaperones
1Anatomy and Physiopathology Division, Department of Clinical and Experimental Sciences, Viale Europa 11, 25123 Brescia, Italy. alessandra.stacchiotti@unibs.it.
Cellular stress responses, involving heat shock proteins and organelle interactions like mitochondria-associated endoplasmic reticulum membranes (MAMs), are crucial for understanding aging and diseases. Targeting endoplasmic reticulum proteostasis and lipid exchange offers therapeutic potential.
Area of Science:
- Molecular Biology
- Cellular Biology
- Biochemistry
Background:
- Heat shock proteins (HSPs) are conserved cellular stress response signals across eukaryotes.
- Mitochondria-associated endoplasmic reticulum membranes (MAMs) play a role in aging and diseases such as obesity, diabetes, and neurodegeneration.
- Endoplasmic reticulum (ER) function and proteostasis are critical for cellular health.
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