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Allergies of the dental pulp
Oral Surgery, Oral Medicine, and Oral Pathology
|December 1, 1978
Summary
Dental pulp inflammation involves immune cells and antibodies, but antibody-mediated allergies are unproven. Cell-mediated allergies and autoimmunity in dental pulp have been reported.
Area of Science:
- Immunology
- Dental Science
- Allergy Research
Background:
- Dental pulp, particularly when inflamed, contains various immune components.
- These include antigens, lymphocytes, plasmocytes, immunoglobulins (IgG, IgM, IgA, IgE), mast cells, histamine, and complement factor C3.
Purpose of the Study:
- To review existing literature on allergies of the dental pulp.
- To differentiate between antibody-mediated and cell-mediated allergic reactions in the dental pulp.
Main Methods:
- Literature review of publications concerning dental pulp allergies.
- Analysis of immunological components present in inflamed dental pulp.
Main Results:
- Inflamed dental pulp contains a complex array of immune mediators and antibodies.
- No conclusive evidence for antibody-mediated allergy (hypersensitivity) of the dental pulp was found.
- Evidence supports the occurrence of cell-mediated allergies, including graft-rejection and contact hypersensitivity, as well as autoimmunity within the dental pulp.
Conclusions:
- While dental pulp exhibits numerous immunological components, antibody-mediated allergies remain unconfirmed.
- Cell-mediated immune responses and autoimmune conditions are recognized phenomena in dental pulp allergy.
- Further research is needed to fully elucidate the mechanisms of dental pulp allergy.