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Updates in the molecular epidemiology and systemic approaches to penile cancer

Jacob J Adashek1, Andrea Necchi2, Philippe E Spiess3

  • 1Department of Internal Medicine, University of South Florida, Moffitt Cancer Center, Tampa, FL.

Urologic Oncology
|May 5, 2019
PubMed

Insights

Penile cancer incidence is rising, but survival rates remain unchanged. This review details current treatments, novel therapeutic targets, and clinical trials for this rare disease.

Area of Science:

  • Oncology
  • Urology

Background:

  • Penile cancer is a rare malignancy with increasing incidence.
  • Despite rising diagnoses, mortality rates for penile cancer have not improved, indicating a need for better treatment strategies.

Purpose of the Study:

  • To review current treatment strategies for penile cancer.
  • To explore potential therapeutic targets and novel modalities.
  • To discuss ongoing clinical trials for penile cancer.

Main Methods:

  • Literature review of current treatments.
  • Analysis of potential therapeutic targets.
  • Overview of ongoing clinical trials.

Main Results:

  • Penile cancer incidence is increasing.
  • Treatment outcomes and survival rates have not significantly improved.
  • Sparse therapeutic options currently exist for penile cancer.

Conclusions:

  • There is a critical need for novel treatment strategies and therapeutic targets in penile cancer.
  • Ongoing clinical trials offer hope for improved patient outcomes.
  • Further research into innovative therapeutic modalities is essential.
Keywords:
Human papilloma virusNovel therapyPenile cancer

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