Decompressive Craniectomy in Children with Severe Traumatic Brain Injury: A Multicenter Retrospective Study and

Marie Manfiotto1, Kevin Beccaria2, Alice Rolland3

  • 1Service de Neurochirurgie, CHU de Nice, Nice, France.

World Neurosurgery
|May 5, 2019
PubMed

Insights

Decompressive craniectomy can lead to good neurologic outcomes in children with severe traumatic brain injury (TBI). Key prognostic factors include age, initial GCS score, and intracranial pressure levels.

Area of Science:

  • Pediatric neurosurgery
  • Pediatric critical care
  • Neurotraumatology

Background:

  • Severe traumatic brain injury (TBI) is a leading cause of childhood disability.
  • Refractory increased intracranial pressure poses a significant therapeutic challenge.
  • The role of decompressive craniectomy in pediatric TBI management requires further definition.

Purpose of the Study:

  • To identify prognostic factors for long-term outcomes in children with severe TBI.
  • To evaluate the efficacy of decompressive craniectomy in pediatric TBI.

Main Methods:

  • Retrospective, multicenter study.
  • Analysis of long-term outcomes in 150 children with severe TBI treated with decompressive craniectomy.
  • Identification of prognostic factors influencing neurological recovery.

Main Results:

  • 62% of children achieved satisfactory neurological outcomes (King's Outcome Scale >3) after a mean follow-up of 3.5 years.
  • Mortality rate was 17%.
  • Prognostic factors included age, initial Glasgow Coma Scale score, mydriasis, maximal intracranial pressure (>30 mm Hg), and Rotterdam score (≥4).

Conclusions:

  • Decompressive craniectomy can result in favorable neurological outcomes for children with severe TBI.
  • Further research is necessary to establish clear guidelines for decompressive craniectomy in pediatric TBI management.
Abstract

Related Concept Videos

Review and Preview01:10

Review and Preview

In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
8.3K
Review and Preview01:13

Review and Preview

Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
10.9K
Traumatic Memory01:20

Traumatic Memory

Emotionally traumatic events often lead to memories that are exceptionally vivid and enduring, sometimes persisting with remarkable clarity throughout an individual's life. A classic example of this phenomenon is a person who survives a car accident. Even years later, they may recall every detail of the event with startling accuracy — the screeching of the tires, the jarring impact, and the acrid smell of burning rubber. Such vividness contrasts sharply with how an individual...
565
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
266
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
287
Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
506