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Updated: Jan 25, 2026

Controlled Cortical Impact Model for Traumatic Brain Injury
Published on: August 5, 2014
Decompressive Craniectomy in Children with Severe Traumatic Brain Injury: A Multicenter Retrospective Study and
Marie Manfiotto1, Kevin Beccaria2, Alice Rolland3
1Service de Neurochirurgie, CHU de Nice, Nice, France.
Insights
Decompressive craniectomy can lead to good neurologic outcomes in children with severe traumatic brain injury (TBI). Key prognostic factors include age, initial GCS score, and intracranial pressure levels.
Area of Science:
- Pediatric neurosurgery
- Pediatric critical care
- Neurotraumatology
Background:
- Severe traumatic brain injury (TBI) is a leading cause of childhood disability.
- Refractory increased intracranial pressure poses a significant therapeutic challenge.
- The role of decompressive craniectomy in pediatric TBI management requires further definition.
Purpose of the Study:
- To identify prognostic factors for long-term outcomes in children with severe TBI.
- To evaluate the efficacy of decompressive craniectomy in pediatric TBI.
Main Methods:
- Retrospective, multicenter study.
- Analysis of long-term outcomes in 150 children with severe TBI treated with decompressive craniectomy.
- Identification of prognostic factors influencing neurological recovery.
Main Results:
- 62% of children achieved satisfactory neurological outcomes (King's Outcome Scale >3) after a mean follow-up of 3.5 years.
- Mortality rate was 17%.
- Prognostic factors included age, initial Glasgow Coma Scale score, mydriasis, maximal intracranial pressure (>30 mm Hg), and Rotterdam score (≥4).
Conclusions:
- Decompressive craniectomy can result in favorable neurological outcomes for children with severe TBI.
- Further research is necessary to establish clear guidelines for decompressive craniectomy in pediatric TBI management.
Background:
Severe traumatic brain injury (TBI) is the most common cause of disability in children. Refractory increased intracranial pressure can be a therapeutic challenge. Decompressive craniectomy can be proposed when medical management is insufficient, but its place is not clearly defined in guidelines. The aim of this study was to identify prognostic factors in children with TBI.
Methods:
We performed a retrospective, multicenter study to analyze long-term outcomes of 150 children with severe TBI treated by decompressive craniectomy and to identify prognostic factors.
Results:
A satisfactory neurologic evolution (represented by a King's Outcome Scale for Childhood Head Injury score >3) was observed in 62% of children with a mean follow-up of 3.5 years. Mortality rate was 17%. Prognostic factors associated with outcome were age, initial Glasgow Coma Scale score, presence of mydriasis, neuromonitoring values (maximal intracranial pressure >30 mm Hg), and radiologic findings (Rotterdam score ≥4).
Conclusions:
This study in a large population confirms that children with severe TBI treated by decompressive craniectomy can achieve a good neurologic outcome. Further studies are needed to clarify the use of this surgery in the management of children with severe TBI.
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