Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA as a Genetic Template02:05

DNA as a Genetic Template

27.4K
Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...
27.4K
DNA as a Genetic Template02:05

DNA as a Genetic Template

9.4K
9.4K
Ligand-Gated Ion Channel Receptor: Gating Mechanism01:30

Ligand-Gated Ion Channel Receptor: Gating Mechanism

3.9K
Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...
3.9K
DNA Replication02:40

DNA Replication

59.0K
DNA replication involves the separation of the two strands of the double helix, with each strand serving as a template from which the new complementary strand is copied.  After replication, each double-stranded DNA includes one parental or “old” strand and one “new” strand. This is known as semiconservative replication. The resulting DNA molecules have the same sequence and are divided equally into the two daughter cells.
Replication in Prokaryotes
DNA replication...
59.0K
Underflow Gates01:30

Underflow Gates

403
Underflow gates are vital for controlling water flow in irrigation canals. The three main types of underflow gates — vertical, radial, and drum gates — serve different purposes while ensuring effective flow management. Vertical gates move up and down, generating a free-flowing water jet; radial gates pivot to regulate the flow; and drum gates rotate for precise adjustments. The flow through these gates is influenced by downstream conditions, resulting in free or drowned outflow.Free and...
403
Complementary DNA01:44

Complementary DNA

31.4K
Overview
31.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Linear trinuclear and tetranuclear Ln(III) compounds aggregated by multidentate Schiff base ligands: insights into the magnetocaloric effect, slow magnetic relaxation behavior and catalytic CO<sub>2</sub> conversion.

Dalton transactions (Cambridge, England : 2003)·2025
Same author

Self-Assembly of Heterometallic [Ln<sup>III</sup> <sub>2</sub>Co<sup>II</sup> <sub>5</sub>] Clusters: Magnetic Properties and Efffcient Conversion of CO<sub>2</sub> with Epoxides and Amines.

Chemistry (Weinheim an der Bergstrasse, Germany)·2025
Same author

Defect-Induced Electron Localization Promotes D<sub>2</sub>O Dissociation and Nitrile Adsorption for Deuterated Amines.

Angewandte Chemie (International ed. in English)·2025
Same author

The survival and outcome of older patients with primary aneurysmal subarachnoid haemorrhage: a 2-year follow-up, multi-centre, observational study.

Age and ageing·2023
Same author

Bifunctional Lanthanide-Based Coordination Polymers: Conversion of CO<sub>2</sub> and Highly Selective Luminescence Sensing for Acetylacetone.

Inorganic chemistry·2023
Same author

Two novel Ln<sub>8</sub> clusters bridged by CO<sub>3</sub><sup>2-</sup> effectively convert CO<sub>2</sub> into oxazolidinones and cyclic carbonates.

Dalton transactions (Cambridge, England : 2003)·2023
Same journal

Corrigendum to "CFPNet-M: A light-weight encoder-decoder based network for multimodal biomedical image real-time segmentation" [Comput. Biol. Med. 154 (2023) 106579].

Computers in biology and medicine·2026
Same journal

ECG arrhythmia classification via wavelet-driven feature extraction and swarm-optimised gradient boosting.

Computers in biology and medicine·2026
Same journal

Electro-osmotic metachronal cilia transport of viscoelastic blood infused with penta-hybrid nanoparticles in an oviduct: Analytical and neural network modeling.

Computers in biology and medicine·2026
Same journal

sEEGnal: an automated EEG preprocessing pipeline evaluated against expert-driven preprocessing.

Computers in biology and medicine·2026
Same journal

Corrigendum to "Integrating experimental biology, computational methods, and artificial Intelligence in anticancer drug discovery: Bridging the translational Gap" [Comput. Biol. Med. 213 (2026) 111832].

Computers in biology and medicine·2026
Same journal

Organ dose optimization for a point-of-care forearm X-ray photon-counting CT.

Computers in biology and medicine·2026
See all related articles

Related Experiment Video

Updated: Jan 25, 2026

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates
09:17

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates

Published on: March 5, 2019

9.2K

Dynamically NAND gate system on DNA origami template.

Zhen Tang1, Zhi-Xiang Yin1, Xia Sun1

  • 1School of Mathematics and Big Data, AnHui University of Science&Technology, Huainan, 232001, AnHui, China.

Computers in Biology and Medicine
|May 5, 2019
PubMed
Summary
This summary is machine-generated.

This study presents a stable DNA origami-based NAND gate system. The system uses DNA input strands and hybridization chain reaction for dynamic logic operations, with results indicated by nanogold particle disassembly.

Keywords:
DNA computingDNA origamiHybridization chain reactionMolecular logic gateNAND gate

More Related Videos

Designing a Bio-responsive Robot from DNA Origami
13:32

Designing a Bio-responsive Robot from DNA Origami

Published on: July 8, 2013

22.8K
Preparation of Mica and Silicon Substrates for DNA Origami Analysis and Experimentation
12:03

Preparation of Mica and Silicon Substrates for DNA Origami Analysis and Experimentation

Published on: July 23, 2015

15.0K

Related Experiment Videos

Last Updated: Jan 25, 2026

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates
09:17

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates

Published on: March 5, 2019

9.2K
Designing a Bio-responsive Robot from DNA Origami
13:32

Designing a Bio-responsive Robot from DNA Origami

Published on: July 8, 2013

22.8K
Preparation of Mica and Silicon Substrates for DNA Origami Analysis and Experimentation
12:03

Preparation of Mica and Silicon Substrates for DNA Origami Analysis and Experimentation

Published on: July 23, 2015

15.0K

Area of Science:

  • Biotechnology
  • Nanotechnology
  • Molecular computing

Background:

  • DNA logic gates are foundational for DNA computing.
  • Developing stable and dynamic molecular logic systems is crucial.

Purpose of the Study:

  • To establish a dynamic NAND gate system utilizing a DNA origami template.
  • To demonstrate a stable and intelligent DNA-based logic system.

Main Methods:

  • Utilizing a DNA origami template for a dynamic NAND gate system.
  • Employing DNA input strands to represent logical values.
  • Implementing a directed hybridization chain reaction (HCR).
  • Identifying results via nanogold particle (AuNPs) disassembly from the template.

Main Results:

  • The system demonstrated stable operation in solution without external reactions.
  • Successful implementation of a dynamic NAND gate logic operation.
  • Visual DSD simulations confirmed the reaction's accuracy and absence of errors.
  • Nanogold particle behavior accurately indicated true (retention) or false (disassembly) outputs.

Conclusions:

  • The developed DNA origami NAND gate system is feasible, stable, and intelligent.
  • This system shows potential for advanced DNA computing applications.
  • The dynamic nature and clear output mechanism offer advantages for molecular logic devices.