Related Experiment Video
Updated: Jan 25, 2026
09:56
Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice
Published on: February 14, 2021
5.9K
Baroreflex stimulation for treating resistant hypertension: ready for the prime-time?
Davide Bolignano1, Giuseppe Coppolino2
1CNR-Institute of Clinical Physiology, Reggio Calabria, 89124, Italy.
Reviews in Cardiovascular Medicine
|May 6, 2019
Summary
Device-based therapies like baroreflex activation therapy (BAT) and endovascular baroreflex amplification (EBA) show promise for managing resistant hypertension. These methods stimulate the carotid baroreflex to improve blood pressure control with few side effects.
Area of Science:
- Cardiology
- Medical Devices
- Hypertension Management
Background:
- Resistant hypertension poses a significant clinical challenge, necessitating novel therapeutic strategies.
- Current management often involves complex multi-drug regimens with limited efficacy for some patients.
Purpose of the Study:
- To review and synthesize evidence on baroreflex activation therapy (BAT) and endovascular baroreflex amplification (EBA) for resistant hypertension.
- To provide an overview of device-based therapies targeting the carotid baroreflex.
Main Methods:
- Systematic review and evidence synthesis of studies on BAT and EBA.
- Analysis of mechanisms involving carotid baroreflex stimulation to modulate autonomic activity.
Main Results:
- Accruing evidence suggests BAT and EBA can improve blood pressure control in resistant hypertension.
- These therapies may reduce the need for antihypertensive medications.
- Reported side effects are generally minimal.
Conclusions:
- Device-based baroreflex stimulation offers a potential alternative for managing resistant hypertension.
- Further data from ongoing randomized controlled trials are needed to establish long-term efficacy and safety.
- Invasive baroreflex therapies require careful consideration for clinical practice.
More Related Videos
04:37Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
702
08:50Brain State-dependent Brain Stimulation with Real-time Electroencephalography-Triggered Transcranial Magnetic Stimulation
Published on: August 20, 2019
15.1K
Related Concept Videos
01:26Ready Mixed Concrete
354
Ready-mixed concrete, also known as pre-mixed concrete, is prepared in a centralized plant and then transported in trucks to construction sites where it is ready for placement. This type of concrete is categorized into central-mixed, truck-mixed (or transit-mixed), and shrink-mixed. Central-mixed concrete is entirely prepared at a plant and moved to the site in agitator trucks that rotate at a speed of 2 to 6 rpm. Truck-mixed concrete, on the other hand, has the ingredients batched at the plant...
354
01:22Resistivity
4.4K
When a voltage is applied to a conductor, an electrical field is generated, and charges in the conductor feel the force due to the electrical field. The current density that results depends on the electrical field and the properties of the material. In some materials, including metals at a given temperature, the current density is approximately proportional to the electrical field. In these cases, the current density can be modeled as:
4.4K
01:19Resistance
5.7K
When a current moves through any conductor, the conductor causes some level of difficulty for the current to flow. The measure of that difficulty is known as the resistance of the material and is represented by R. Every material has its own resistance. In the case of conductors, heat is emitted whenever a current passes through them. Resistance depends on the resistivity of the material. Resistivity is a characteristic of the material used to fabricate electrical components, whereas the...
5.7K
01:28Hypertension I: Introduction
793
Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
793
01:29Hypertension II: Pathophysiology
879
Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
879
01:23Hypertension V: Nursing Management
392
The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
392