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Related Experiment Video

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Studying Orthodontic Tooth Movement in Mice
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Interfacing the basic sciences and clinical orthodontics.

Rishma Shah1, John Paul Zermeno1

  • 1Department of Orthodontics, UNC-CH Adams School of Dentistry, Chapel Hill, NC, USA.

Journal of Orthodontics
|May 7, 2019
PubMed
Summary
This summary is machine-generated.

Translational research bridges basic science discoveries with clinical applications. Orthodontists use this approach, including animal models and clinical trials, to develop faster, safer therapies for better patient outcomes.

Keywords:
Translational researchorthodontic tooth movementroot resorption

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Area of Science:

  • Orthodontics
  • Translational Science
  • Biomedical Research

Background:

  • Orthodontic treatment aims to improve patient outcomes and experiences.
  • There is a continuous need for faster, safer, and alternative clinical therapies in orthodontics.

Purpose of the Study:

  • To highlight the role of translational research in advancing orthodontic care.
  • To emphasize the application of basic science findings to clinical practice.

Main Methods:

  • Utilizing benchtop research to generate foundational knowledge.
  • Employing translational research involving animal models.
  • Conducting robust clinical trials to validate findings.

Main Results:

  • Translational research provides a pathway to answer clinical questions in orthodontics.
  • This research facilitates the development of improved orthodontic treatments.

Conclusions:

  • Translational research is crucial for enhancing orthodontic therapies.
  • Integrating basic science with clinical application leads to significant advancements in patient care.