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Related Concept Videos

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Multicellular organisms employ a variety of ways for cells to communicate with each other. Gap junctions are specialized proteins that form pores between neighboring cells in animals, connecting the cytoplasm between the two, and allowing for the exchange of molecules and ions. They are found in a wide range of invertebrate and vertebrate species, mediate numerous functions including cell differentiation and development, and are associated with numerous human diseases, including cardiac and...
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The cytoplasm of adjacent animal cells can exchange small molecules, ions, and secondary messengers via the communication channels which form the gap junctions. These junctions comprise a few hundred to thousands of molecular channels, each made of two halves, called the connexon hemichannel. A connexon is a hexamer of six transmembrane connexin proteins, which assemble radially, thus forming a pore or channel in the center. One connexon hemichannel docks with a corresponding connexon on the...
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The frequency-domain technique, commonly used in analyzing and designing feedback control systems, is effective for linear, time-invariant systems. However, it falls short when dealing with nonlinear, time-varying, and multiple-input multiple-output systems. The time-domain or state-space approach addresses these limitations by utilizing state variables to construct simultaneous, first-order differential equations, known as state equations, for an nth-order system.
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Related Experiment Video

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A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
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Mind the gap: A novel technique for space closure - a case report.

Rupal Shah1, Mohammad O Sharif2, Daljit S Gill1

  • 11 Department of Orthodontics, Eastman Dental Hospital, London, UK.

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|May 7, 2019
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Summary

Severe hypodontia presents challenges in managing dental arch spaces and anchorage. A novel four-bracket technique effectively closed a midline diastema with bodily tooth movement and maintained root parallelism.

Keywords:
anchorage controldiastema closurefixed appliancessevere hypodontia

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Area of Science:

  • Dentistry
  • Orthodontics
  • Dental Anomalies

Background:

  • Severe hypodontia poses management challenges due to significant dental arch spaces and compromised anchorage.
  • Lack of permanent teeth complicates orthodontic treatment planning and execution.

Observation:

  • A 14-year-old patient with severe hypodontia presented with a 7-mm midline diastema requiring closure for partial denture provision.
  • Initial attempts at space closure using a standard archwire resulted in undesirable incisor crown tipping.

Findings:

  • A novel technique utilizing a four-bracket system (two brackets per central incisor) was implemented for diastema closure.
  • This system employed dual stainless steel archwires and elastomeric chains, enabling bodily tooth movement and superior anchorage control.
  • Excellent root parallelism was achieved during the 7-mm midline diastema closure.

Implications:

  • This innovative four-bracket technique offers a viable solution for diastema closure in severe hypodontia cases with limited anchorage.
  • It facilitates controlled bodily tooth movement, ensuring optimal root parallelism and aiding in prosthetic rehabilitation.
  • The technique enhances treatment predictability and outcomes for patients with complex dental anomalies.