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Updated: Jan 25, 2026

Frailty Assessment in an Aging Mouse Model
Published on: September 23, 2025
Frailty assessment: from clinical to radiological tools
Itay Bentov1, Stephen J Kaplan2, Tam N Pham3
1Department of Anesthesiology and Pain Medicine, Harborview Medical Center, University of Washington, Seattle, WA, USA.
Frailty assessment is crucial for older surgical patients. This review explores clinical tools and proposes using radiological imaging as an objective method to improve preoperative planning and patient outcomes.
Area of Science:
- Gerontology
- Anesthesiology
- Radiology
Background:
- Frailty is a syndrome of physiological decline, increasing vulnerability in adults.
- Identifying frailty aids in preoperative risk stratification and perioperative planning for older surgical patients.
- Current clinical frailty assessment tools lack standardization for widespread clinical use.
Purpose of the Study:
- To highlight the importance of frailty assessment by anesthesiologists.
- To review existing clinical tools for frailty diagnosis.
- To propose radiological imaging as an objective surrogate for frailty assessment.
Main Methods:
- Review of existing literature on frailty assessment tools.
- Exploration of radiological modalities (CT, ultrasonography) as objective frailty markers.
- Discussion of the role of anesthesiologists in implementing new assessment methods.
Main Results:
- Numerous clinical frailty assessment tools exist but lack a standardized approach.
- Radiological imaging is frequently performed preoperatively, offering opportunistic assessment.
- Objective surrogate markers from imaging can supplement subjective clinical evaluations.
Conclusions:
- Anesthesiologists play a key role in identifying frailty in older surgical patients.
- Radiological imaging presents a novel and expanding approach for objective frailty assessment.
- Utilizing imaging can significantly improve preoperative risk stratification and perioperative planning.
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