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Updated: Jan 25, 2026

Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease
Published on: September 20, 2018
[Correlation between ischemic myocardial injury and inflammatory reaction, and anti-inflammatory effect of
Jing Yuan1, Jun-Meng Wang1, Yun Cai1
1Key Laboratory of Integrated Acupuncture and Medicine of Chinese Ministry of Education, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Abstract:
The inflammatory reaction induced by ischemic myocardial injury (IMI) is divided into three phases, i.e. the inflammatory phase, the fibrous proliferative phase and the stable phase. The appropriate inflammatory reaction effectively removes the fragments of myocardial cells, which is the essential phase in the pathological progression of myocardial ischemia (MI). However, the excessive inflammatory reaction may aggravate the myocardial injury. For this reason, the immediate control of the post-injury inflammatory reaction is the principal therapeutic measure and the research hotspot at the present. Acupuncture intervention has been demonstrated to have positive roles in relieving MI and inflammatory reaction by suppressing myocardial inflammatory cytokines (suppressing IL-1β, TNF-α, IL-8, etc.), adjusting inflammatory reaction pathway (NF-κB signaling, TGF-β, etc.)and activating cholinergic anti-inflammatory pathway. Therefore, it is feasible to explore the underlying mechanism of acupuncture therapy in protecting ischemic myocardium based on anti-inflammatory efficacy.
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