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Updated: Jan 25, 2026

Author Spotlight: Emerging Technologies and Advanced Tools for Decoding Metabolomics Data Analysis
Published on: November 10, 2023
Metabolomics of Male Infertility: A New Tool for Diagnostic Tests
Bahareh Mehrparavar1, Arash Minai-Tehrani2, Babak Arjmand3,4
1Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Abstract:
Infertility is a major health issue worldwide. Males and females contribute equally to this problem. Diagnostic semen analysis fails to identify 50% of male infertility disorders. In this regard, metabolomics as a new field of omics has been suggested to have the potential of solving and diagnosis of the male infertility problems. Metabo-lome has a history of around 20 years. However, there are only limited metabolomics studies carried out regarding male infertility. In this review, the current metabolomics researches that have been done in infertile men were reviewed. Based on our own results, using human seminal plasma for metabolomics studies is highly recommended to find potential biomarkers and developing diagnosis tests for detection of main deficiencies in infertile men.
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