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Updated: Jan 25, 2026

Development of an Innovative LED-based Illumination Device for In Vitro Application of Photodynamic Therapy with Rose Bengal
Published on: September 12, 2025
Application and performance evaluation of a cost-effective vis- LED based fluidized bed reactor for the treatment of
Anupama Surenjan1, Thalappil Pradeep2, Ligy Philip1
1Department of Civil Engineering, Indian Institute of Technology Madras, Chennai, 600036, India.
Abstract:
Visible light induced photocatalysis is considered as one of the most potential technologies which can achieve new levels of sustainability in water treatment. The current study explores the performance of immobilized visible light active catalyst on inert media for light driven catalysis of pharmaceuticals. These coated media is used in a continuous flow fluidized column reactor equipped with spirally arranged visible Light Emitting Diodes (LEDs) as irradiation source. The treatment efficiency of the system is evaluated for the removal of pharmaceutical drugs such as carbamazepine, diclofenac and ibuprofen. For the present study, system parameters such as light intensity and flow rate are optimized for maximum removal rate. The system shows complete elimination of the pharmaceuticals under the given experimental conditions. Complete mineralization of the target compounds are confirmed by TOC analysis. Recyclability is an important attribute for full scale commercialization of a treatment technology. An investigation on the reusability study of the photocatalyst displayed no significant reduction in the removal efficiency for a run of six cycles, hence rendering the photocatalyst reusable. The results acquired indicate an immense potential for scaling up the photoreactor as a sustainable tertiary treatment technology in water treatment plants.
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