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Updated: Jan 25, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
Electronic Neurostatus-EDSS increases the quality of expanded disability status scale assessments: Experience from
Marcus D'Souza1, Antti Heikkilä2, Johannes Lorscheider3
1Neurology, Departments of Medicine, Clinical Research, Biomedicine and Biomedical Engineering, University Hospital Basel, Basel, Switzerland/NeuroCure Clinical Research Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.
Background:
The Neurostatus-eEDSS is an electronic tool providing automated real-time feedback on inconsistencies of Neurostatus-EDSS calculations.
Objective:
To analyze the performance of the Neurostatus-eEDSS in two multicenter phase 3 multiple sclerosis (MS) trials.
Methods:
All assessments captured with the Neurostatus-eEDSS web service during a period of 2.5 years were analyzed.
Results:
Of the total 10,789 assessments, 40.1% had inconsistencies after first entry, reduced to 22.1% due to the real-time feedback. The entire checking process resulted in a change of the expanded disability status scale (EDSS) score in 14.8% of the assessments.
Conclusion:
The Neurostatus-eEDSS can increase consistency and reliability of EDSS assessments in clinical MS trials.
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