Related Experiment Video
Updated: Jan 25, 2026

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
Published on: April 3, 2016
Retinal damage thresholds from 100-millisecond laser radiation exposure at 1319 nm: a comparative study for rabbits
Luguang Jiao1,2, Jiarui Wang1, Jinggeng Yang1
1Beijing Institute of Radiation Medicine, Beijing, 100850, China.
Abstract:
With the widespread use of high-power laser systems in the wavelength spectrum between 1300 and 1400 nm, the risk of ocular damage becomes more serious and concerning. Existing ocular bio-effects studies have revealed unique damage characteristics, the damage mechanisms involved, and the trends of damage thresholds in this wavelength range. However, the influence of ocular axial length on retinal damage thresholds has not been investigated quantitatively. In this paper, using a 1319 nm continuous-wave laser, the in-vivo retinal damage thresholds were determined for two groups of chinchilla grey rabbits with the ocular axial lengths of 15.97 and 17.25 mm, respectively. The incident corneal irradiance diameter was fixed at 5 mm and the exposure duration was 0.1 s. The determined ED50 values at 24-h post-exposure for the axial lengths of 15.97 and 17.25 mm were 1.06 and 1.79 J, respectively. Detailed analysis revealed that a sufficient margin existed between the damage threshold and MPE for adult humans, but for the newborn eyes, the safety factor may be less than 2.3.
Related Concept Videos
Biological Effects of Radiation
Interference: Path Lengths
Two special sources may be considered when they are in phase. This can be easily achieved by feeding the two sources from the same source. An example would be synchronizing the two speakers by feeding them with the same source, such as the sound waves produced by a tuning fork. This setup ensures that the two sources have the same frequency and are...
Bond Energies and Bond Lengths
Axial and Appendicular Muscles
Axial Muscles
Axial muscles, situated along the body's midline, are intricately connected to the axial skeleton, which includes the skull, spine, ribs, and sternum. These muscles facilitate facial expressions and...
General Case of Eccentric Axial Loading
Consider a member subjected to equal and opposite forces that are applied along a line that does not coincide with the member's neutral axis. In unsymmetrical...
Overview of the Axial Skeleton
The axial skeleton of the...

