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Brain abscess in pediatric age: a review

Chiara Mameli1, Teresa Genoni2, Cristina Madia2

  • 1Department of Pediatrics, V. Buzzi Childrens' Hospital, University of Milan, Milan, Italy. chiara.mameli@unimi.it.

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|May 8, 2019
PubMed

Insights

Pediatric brain abscess is a rare, serious infection. While incidence and mortality have decreased due to better treatments, there

Area of Science:

  • Neurology
  • Infectious Diseases
  • Pediatrics

Background:

  • Pediatric brain abscess is a rare but severe infection.
  • High morbidity and mortality rates are associated with this condition.
  • Specific risk factors often predispose children to brain abscess.

Purpose of the Study:

  • To review the current state of the art regarding the epidemiology, diagnosis, and treatment of pediatric brain abscess.
  • To synthesize existing literature on brain abscess management in children.

Main Methods:

  • A comprehensive literature review was conducted using PubMed.
  • Keywords included "brain abscess," "cerebral abscess," "brain infection," and related terms.
  • Original articles, case reports, and reviews were included.

Main Results:

  • Incidence and mortality of brain abscess have declined due to advances in antibiotic therapy, neurosurgery, and vaccinations.
  • Conflicting data exist regarding optimal diagnostic and therapeutic strategies due to a lack of established guidelines.
  • Epidemiological trends may shift with evolving risk factors.

Conclusions:

  • Further multicentric prospective studies are needed to establish robust evidence for brain abscess management.
  • Standardized diagnostic-therapeutic pathways are crucial for improving patient outcomes.
  • Ongoing monitoring of epidemiological changes is important for adapting treatment strategies.
Abstract

Keywords:
Brain abscessCentral nervous system infectionsChildrenIntracranial infection

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