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Brain abscess in pediatric age: a review
Chiara Mameli1, Teresa Genoni2, Cristina Madia2
1Department of Pediatrics, V. Buzzi Childrens' Hospital, University of Milan, Milan, Italy. chiara.mameli@unimi.it.
Summary
Pediatric brain abscess is a rare, serious infection. While incidence and mortality have decreased due to better treatments, there
Area of Science:
- Neurology
- Infectious Diseases
- Pediatrics
Background:
- Pediatric brain abscess is a rare but severe infection.
- High morbidity and mortality rates are associated with this condition.
- Specific risk factors often predispose children to brain abscess.
Purpose of the Study:
- To review the current state of the art regarding the epidemiology, diagnosis, and treatment of pediatric brain abscess.
- To synthesize existing literature on brain abscess management in children.
Main Methods:
- A comprehensive literature review was conducted using PubMed.
- Keywords included "brain abscess," "cerebral abscess," "brain infection," and related terms.
- Original articles, case reports, and reviews were included.
Main Results:
- Incidence and mortality of brain abscess have declined due to advances in antibiotic therapy, neurosurgery, and vaccinations.
- Conflicting data exist regarding optimal diagnostic and therapeutic strategies due to a lack of established guidelines.
- Epidemiological trends may shift with evolving risk factors.
Conclusions:
- Further multicentric prospective studies are needed to establish robust evidence for brain abscess management.
- Standardized diagnostic-therapeutic pathways are crucial for improving patient outcomes.
- Ongoing monitoring of epidemiological changes is important for adapting treatment strategies.
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