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Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
Published on: August 19, 2021
Type-II endometrial cancer: role of adipokines
Kusuma Kumari Garikapati1, V V V Ravi Kiran Ammu1, Praveen T Krishnamurthy2
1Department of Pharmacology, JSS College of Pharmacy (A Constituent College of JSS Academy of Higher Education & Research), Ooty, Tamil Nadu, 643001, India.
Background:
Type-II endometrial cancer is an estrogen independent and one of the most lethal types of cancer having poor prognosis. Adipokines play a crucial role in the triggering Type-II EMC. In addition, adipokines modulators, therefore, may have beneficial effects in the treatment of Type-II endometrial cancer, which was clinically evidenced.
Areas Covered:
This review presents the role of various adipokines involved and also the suitable modulators to treat Type-II endometrial cancer.
Conclusion:
In the present review, we try to discuss the role of individual adipokines in the pathogenesis of Type-II endometrial cancer, and also the possible beneficial effects of adipokines modulator in the treatment of Type-II endometrial cancer.
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