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Updated: Jan 25, 2026

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Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography
Published on: August 11, 2016
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Diffusion weighted imaging evidence of extra-callosal pathways for interhemispheric communication after complete
Jason S Nomi1, Emily Marshall2, Eran Zaidel3,4
1Department of Psychology, University of Miami, P.O. Box 248185-0751, Coral Gables, FL, 33124, USA. jxn131@miami.edu.
Brain Structure & Function
|May 8, 2019
Summary
Split-brain patients show enhanced white matter integrity in specific cerebellar pathways, suggesting anatomical compensation for severed interhemispheric connections. This may explain their preserved cognitive functions despite the lack of a corpus callosum.
Area of Science:
- Neuroscience
- Neuroanatomy
- Cognitive Neurology
Background:
- White matter integrity is crucial for cognitive processing.
- The corpus callosum is the primary white matter bundle connecting the cerebral hemispheres.
- Split-brain patients, lacking the corpus callosum, often retain cognitive abilities, suggesting compensatory mechanisms.
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