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Choroid Plexus Carcinoma in Adults: Two Case Reports
Taehoon Kim1, Mee Rim Park2, Eun Kyeong Hong3
1Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.
Brain Tumor Research and Treatment
|May 8, 2019
Summary
This study details two rare adult choroid plexus carcinoma (CPC) cases, highlighting varied presentations and outcomes. Understanding these distinct progressions aids in diagnosing and treating adult-onset CPC.
Area of Science:
- Neuro-oncology
- Pediatric and Adult Brain Tumors
Background:
- Choroid plexus tumors are rare, typically pediatric intraventricular brain tumors.
- Increased intracranial pressure is a common clinical presentation.
- Cerebrospinal fluid dissemination is a characteristic progression.
Observation:
- Two rare adult choroid plexus carcinoma (CPC) cases with distinct clinical courses are presented.
- Case 1: A 40-year-old male with multiple intraventricular masses, refractory to treatment, progressed to spinal dissemination and expired within a year.
- Case 2: A 49-year-old female presented with visual disturbance, diagnosed with CPC, and has remained recurrence-free for 10 months post-treatment.
Findings:
- Adult-onset CPC exhibits diverse clinical presentations and prognoses.
- Treatment response varied significantly between the two presented adult CPC cases.
- Spinal dissemination occurred in one adult CPC case, underscoring aggressive potential.
Implications:
- These cases offer valuable insights into the diagnosis and management of rare adult choroid plexus tumors.
- Recognizing varied presentations is crucial for timely and appropriate intervention in adult CPC.
- Further research into adult CPC is warranted to improve therapeutic strategies.
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