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Three new diterpenes from Dysoxylum lukii and their NO production inhibitory activity
Pu-Zhao Zhang1, Ya-Mei Zhang2, Yuan Lin3
1Key Laboratory Modern Preparation of TCM, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China.
Abstract:
Three new diterpenes were isolated from the stems of Dysoxylum lukii Merr and characterized on the basis of spectral data. Neoclerod-13Z-ene-3α, 4β, 15-triol (3) exhibited the inhibition of lipopolysaccharide-induced nitric oxide production in RAW264.7 macrophages with an IC50 value of 25.49 μM.[Formula: see text].
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