Related Experiment Video
Updated: Jan 25, 2026

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
Published on: September 26, 2022
Foot allergic contact dermatitis to mixed dialkyl thioureas
Chandler W Rundle1, Tracy Funk2,3, Ross M Brockman2
1School of Medicine, Loma Linda University, Loma Linda, California.
Abstract:
A 12-year-old boy presented with severe, bilateral foot dermatitis. Extended patch testing was performed, revealing a significant positive reaction to mixed dialkyl thioureas. A thorough review of his history revealed that he was likely being exposed through his neoprene taekwondo shoes. After implementation of allergen avoidance measures, his dermatitis resolved. This case emphasizes awareness of potential allergen exposures and offers helpful avoidance strategies.
Related Concept Videos
Allergic Reactions
Muscles of the Leg that Move the Foot and Toes
Anterior Compartment
The anterior compartment includes muscles that contribute to the dorsiflexion of the foot. This compartment houses the tibialis anterior, extensor hallucis longus, and extensor digitorum longus muscles....
Allergic Drug Reactions
Contact-dependent Signaling
Gap Junctions
In animal cells, gap junctions are formed...
Contact Angle
The adhesive force is the molecular force between molecules of different materials, that is, between the molecules of the solid and the liquid. The cohesive...
Mixing Concrete

