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Acute pancreatitis in childhood-onset systemic lupus erythematosus: Case report
1Departamento de Nefrología Pediátrica, Hospital Xinhua afiliado a la Facultad de Medicina de la Universidad de Shanghái Jiao Tong, China. liyufeng@xinhuamed.com.cn.
Insights
Systemic lupus erythematosus (SLE) can cause pancreatitis, a serious condition. This case highlights successful treatment of SLE-associated pancreatitis in a child using immunosuppressants after steroid therapy.
Area of Science:
- Immunology
- Gastroenterology
- Pediatrics
Background:
- Systemic lupus erythematosus (SLE) is a complex autoimmune disease affecting multiple organs.
- Lupus pancreatitis, a complication of SLE, is a significant cause of acute abdomen in affected patients.
- While rare, pancreatitis in SLE can be life-threatening if not managed promptly.
Abstract:
Systemic lupus erythematosus (SLE) is a multisystem disease with protean manifestations. Lupus pancreatitis is the second most common disease associated with SLE-related acute abdomen. Although acute pancreatitis is rare it is clinically important because this condition can be life threatening if not treated promptly. Here, we report a case of a 10-year-old girl who developed SLE-associated pancreatitis after steroids therapy that was subsequently complicated by fungal septicaemia. Her clinical symptoms and signs markedly improved after administration of glucocorticoids and cyclophosphamide.
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