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Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders
Published on: April 14, 2017
Editorial: Conduct Disorder as a Neurodevelopmental Condition: White Matter Brain Microstructure and the Importance
1Erasmus Medical Center, Rotterdam, The Netherlands.
Abstract:
Although conduct disorder (CD) is a prevalent mental disorder in young people, relatively little research funding is allocated to investigating its etiology.1 More funding for investigation is needed, as the presence of CD can greatly affect a young person's life across various domains, but can also impact their family, peers, and society at large. A better understanding of the neurodevelopment of CD can help tailoring treatment and prevention strategies. Furthermore, as we know that CD symptoms vary across affected individuals, the corresponding neural correlates might also be different for people with different symptom levels. Important factors to take into consideration here include gender; comorbidity, and distinct symptom patterns, such as the presence of callous-unemotional traits.
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