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Updated: Jan 25, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

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The Effects of Balloon-Guide Catheters on Outcomes after Mechanical Thrombectomy in Acute Ischemic Strokes : A

Jun Hyong Ahn1, Steve S Cho2, Sung-Eun Kim3

  • 1Department of Neurosurgery, Hallym University College of Medicine, Chuncheon, Korea.

Journal of Korean Neurosurgical Society
|May 8, 2019
PubMed

Insights

Balloon-guide catheters (BGC) improve recanalization during mechanical thrombectomy for acute ischemic stroke. However, BGC did not significantly reduce distal emboli, and further research is needed to clarify their role.

Area of Science:

  • Neurology
  • Interventional Neuroradiology
  • Cardiovascular Research

Background:

  • Mechanical thrombectomy is a key treatment for acute ischemic stroke.
  • Balloon-guide catheters (BGC) are hypothesized to improve outcomes by enhancing recanalization and reducing distal emboli.

Purpose of the Study:

  • To evaluate the impact of balloon-guide catheters (BGC) on mechanical thrombectomy outcomes in acute ischemic stroke patients.

Main Methods:

  • A systematic review and meta-analysis of studies published between January 2010 and February 2018 from major databases.
  • Included seven articles with 2223 patients, utilizing random-effects modeling, meta-regression, and bias correction methods.

Main Results:

  • Mechanical thrombectomy with BGC was associated with significantly higher successful recanalization rates (OR, 1.632).
  • BGC use did not significantly decrease distal emboli, even after bias correction (adjusted OR, 1.165).
  • Good clinical outcomes were more frequent in the BGC group (OR, 1.886), with no significant difference in symptomatic intracranial hemorrhage or mortality.

Conclusions:

  • Balloon-guide catheters enhance recanalization rates in mechanical thrombectomy for acute ischemic stroke.
  • Evidence does not support a significant reduction in distal emboli with BGC use.
  • Publication bias and heterogeneity warrant cautious interpretation; individual patient data meta-analyses are recommended for definitive conclusions.
Abstract

Keywords:
Meta-analysisStrokeThrombectomy

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