Noteworthy Literature Published in 2018 for Thoracic Organ Transplantation

Justin N Tawil1, Benjamin A Adams2, Alina Nicoara3

  • 11 Medical College of Wisconsin, Milwaukee, WI, USA.

Insights

Reviewing 2018 publications for cardiothoracic transplant anesthesiologists, this summary highlights organ donor expansion strategies, post-transplant outcomes, extracorporeal support, and perioperative risk mitigation for improved patient care.

Area of Science:

  • Anesthesiology
  • Transplantation Medicine
  • Cardiothoracic Surgery

Background:

  • Review of key publications from 2018 relevant to cardiothoracic transplant anesthesiology.
  • Focus on advancements in organ donor management and utilization.

Purpose of the Study:

  • To summarize significant developments and research in cardiothoracic transplantation from 2018.
  • To inform cardiothoracic transplant anesthesiologists about emerging strategies and outcomes.

Main Methods:

  • Literature review of publications from 2018.
  • Analysis of strategies for expanding donor organ availability.
  • Examination of post-transplant outcomes and risk models.
  • Assessment of extracorporeal support and allocation criteria.

Main Results:

  • Highlighted strategies for increasing donor organ availability, including improved donor management, use of increased-risk donors, ex vivo perfusion, and donation after cardiac death.
  • New data-driven risk models for assessing post-transplant outcomes beyond mortality.
  • Prominent theme of extracorporeal support in cardiothoracic transplantation.
  • Implementation of revised adult heart allocation criteria for objectivity and transparency.
  • Identification of frailty and prehabilitation as key targets for perioperative risk mitigation.

Conclusions:

  • Significant advancements in 2018 have expanded donor organ availability and refined post-transplant outcome assessment.
  • Innovations in extracorporeal support and allocation criteria are transforming cardiothoracic transplantation.
  • Focus on comprehensive perioperative risk mitigation, including frailty and prehabilitation, is crucial for improving patient outcomes.

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