Asymmetric Septal Hypertrophy in Appropriate for Gestational Age Infants Born to Diabetic Mothers
Ma Martha Vela-Huerta1, Norma Amador-Licona2, Helena Victoria Orozco Villagomez1
1Department of Neonatology, Hospital General de Leon, Leon: Mexico.
Objective:
To compare the frequency of asymmetric septal hypertrophy in appropriate for gestational age infants born to diabetic mothers with those born to non-diabetic mothers.
Methods:
We compared 38 full term infants born to diabetic mothers with 85 full term infants of non-diabetic mothers. 2-D echocardiography was obtained in the first 24 hours after birth.
Results:
Asymmetric septal hypertrophy was only present in infants born to diabetic mothers (50% vs. 0%; P<0.001). Intraventricular septum thickness and intraventricular septum/posterior wall of the left ventricle ratio was also significantly higher in the first group (P<0.001). We found no correlation between mother´s glycated hemoglobin levels and intraventricular septum thickness in newborns.
Conclusion:
Asymmetric septal hypertrophy is a common finding in infants born to diabetic mothers, even if they are appropriate for gestational age.
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