Related Experiment Video
Updated: Jan 25, 2026
08:39
Quantifying Leukocyte Egress via Lymphatic Vessels from Murine Skin and Tumors
Published on: January 7, 2019
9.1K
Histomorphologic Profile of Skin Tumors
Rupendra Thapa1, Pranita Gurung1, Suspana Hirachand1
1Department of Pathology, Kathmandu Medical College Teaching Hospital, Sinamangal, Kathmandu, Nepal.
JNMA; Journal of the Nepal Medical Association
|May 9, 2019
Summary
This study analyzed 108 skin tumors in Nepal, finding keratinocytic tumors to be most common. Accurate histopathological diagnosis is crucial for effective skin tumor management and prognosis.
Area of Science:
- Dermatopathology
- Oncology
Background:
- Skin tumors present a significant clinical challenge in Nepal.
- Accurate diagnosis and classification are vital for patient prognosis and treatment strategies.
Purpose of the Study:
- To determine the frequency of various histological types of skin tumors.
- To correlate clinicopathologic profiles with tumor types.
- To stage malignant skin tumors.
Main Methods:
- A descriptive, cross-sectional study was conducted from February 2015 to January 2017.
- 108 skin tumor biopsies were analyzed using Hematoxylin and Eosin staining.
- Standard histopathological processing techniques were employed.
Main Results:
- Out of 108 cases, 68 (62.97%) were benign and 40 (37.03%) were malignant skin tumors.
- Keratinocytic tumors were the predominant type in both benign and malignant categories.
- Clinicopathologic correlation and staging data were collected.
Conclusions:
- Histopathological examination is the definitive method for diagnosing skin tumors.
- Emphasizing the staging of malignant tumors in biopsy specimens is essential for predicting patient outcomes.
- This study highlights the importance of histopathology in managing skin tumors in the Nepalese population.
More Related Videos
Related Concept Videos
02:24Ribosome Profiling
4.1K
Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
4.1K
01:30Skin Cancer
5.8K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.8K
01:16Sensory Functions of the Skin
8.0K
The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
8.0K
01:23Skin Diseases and Disorders
5.2K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.2K
01:12Taping Over Different Ground Profiles
358
Taping over varying ground profiles requires careful adaptation to achieve accurate measurements. On smooth, level ground with minimal vegetation, the tape can rest directly on the ground. Here, the taping team, typically consisting of a head and a rear tapeman, coordinates their positions with clear communication. The rear tapeman holds the tape at the starting point and guides the head tapeman toward a range pole placed beyond the endpoint, using hand or voice signals to ensure alignment.On...
358
01:23Role of Skin in Vitamin D Synthesis
7.7K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
7.7K