Determination of Varying Group Sizes for Pooling Procedure
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Updated: Jan 25, 2026

Quantitative Analysis of Synaptic Vesicle Pool Replenishment in Cultured Cerebellar Granule Neurons using FM Dyes
Published on: November 11, 2011
Wenjun Xiong1, Hongyu Lu1, Juan Ding1
1School of Mathematics and Statistics, Guangxi Normal University, Yucai Road 15, Guilin 541004, China.
Abstract:
Pooling is an attractive strategy in screening infected specimens, especially for rare diseases. An essential step of performing the pooled test is to determine the group size. Sometimes, equal group size is not appropriate due to population heterogeneity. In this case, varying group sizes are preferred and could be determined while individual information is available. In this study, we propose a sequential procedure to determine varying group sizes through fully utilizing available information. This procedure is data driven. Simulations show that it has good performance in estimating parameters.
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