[Epigastralgia revealing primary pancreatic large B-cell lymphoma in a young patient: about a case]
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Updated: Jan 25, 2026

A Simple and Rapid Method for Simultaneous Isolation of Primary Islets and Primary Pancreatic Acinar Cells from Mice
Published on: January 9, 2026
Benmoussa Amine1, Lasri Najat1, Tazi Ilias1
1Service d'Hématologie CHU Mohammed VI Marrakech, Faculté de Médecine et de Pharmacie Cadi Ayyad, Maroc.
Abstract:
Primitive malignant pancreatic non-Hodgkin's lymphoma (NHL) is an extremely rare site of extranodal NHL, accounting for less than 0.7% of all NHLs and less than 0.5% of malignant pancreatic tumors. It mainly affects the elderly and very rarely the young subject (hence the interest in our case). Clinical diagnosis is difficult because it mimics pancreatic adenocarcinoma and chronic pancreatitis. We report the case of a 25 year old patient, treated for diffuse primary pancreatic large B-cell NHL revealed by epigastralgia with fulminating jaundice characterised by acute onset associated with alteration of the general state. NHL was diagnosed by biopsy of the duodeno-pancreatic cavity. Diagnosis and early treatment of these aggressive tumors enable remarkable improvements in prognosis.
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