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Porcine Model of Infrarenal Abdominal Aortic Aneurysm
Published on: November 21, 2019
Management of Chronic Disseminated Intravascular Coagulation Associated with Aortic Aneurysm/Dissection
Shigeru Koba1, Tomoya Yamaguchi1, Kenji Miki1
1Department of Internal Medicine, Uji-Tokushukai Medical Center, Uji 611-0041, Japan.
Insights
Chronic disseminated intravascular coagulation (DIC) in elderly patients may indicate aortic aneurysm or dissection. Early diagnosis and appropriate nonsurgical treatment are crucial for managing this complex condition.
Area of Science:
- Internal Medicine
- Vascular Surgery
- Hematology
Background:
- Disseminated intravascular coagulation (DIC) is a severe condition with both clotting and bleeding risks.
- Chronic DIC has been linked to aortic aneurysm and dissection, particularly in older individuals.
Observation:
- This report details four elderly patients with chronic DIC associated with aortic aneurysm/dissection.
- The study highlights the clinical features and treatment of these complex cases.
Findings:
- Aortic aneurysm/dissection should be considered in elderly patients presenting with unexplained bleeding tendencies and DIC.
- Nonsurgical management strategies were explored for these patients.
Implications:
- Recognizing the association between chronic DIC and aortic pathology is vital for accurate diagnosis in elderly patients.
- Tailored nonsurgical treatment approaches are recommended for managing chronic DIC in the context of aortic aneurysm/dissection.
Abstract:
Disseminated intravascular coagulation (DIC) is a systemic life-threatening process that can cause thrombosis and hemorrhage. Chronic DIC has been associated with aortic aneurysm/dissection. Aortic aneurysm/dissection should be included in the differential diagnosis of elderly patients with hemorrhagic diathesis due to DIC of uncertain etiology. Treatment depends on various factors, including the severity of underlying disease, extent of DIC, and patient comorbidities, as well as the ability of the patient to maintain activities of daily living once discharged from the hospital. This report describes the clinical characteristics of four elderly patients with chronic DIC associated with aortic aneurysm/dissection who were treated in our institution. We also offer the recommendations around most appropriate nonsurgical treatment of these patients.
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