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Expression, Purification, and Antimicrobial Activity of S100A12
Published on: May 13, 2017
Multifactor Assessment of Non-Antimicrobial Soap Performance
James Bingham1, Todd J Cartner1, Patricia A Mays Suko2
1Research and Development, GOJO Industries, Inc., Akron, Ohio.
A new non-antimicrobial soap effectively removes more Staphylococcus aureus from hands than reference soaps. It also demonstrates comparable skin compatibility, making it a viable alternative for hand hygiene.
Area of Science:
- Microbiology
- Dermatology
- Public Health
Background:
- Soap efficacy relies on microbial removal and skin compatibility.
- Assessing non-antimicrobial soaps is crucial for hygiene practices.
Purpose of the Study:
- To compare a non-antimicrobial soap against reference soaps for microbial removal and skin compatibility.
- To evaluate the effectiveness of a novel non-antimicrobial soap formulation.
Main Methods:
- Benchmarking a non-antimicrobial soap against two reference soaps.
- Assessing Staphylococcus aureus removal from nonwetted hands.
- Evaluating skin barrier function using established dermatological metrics.
Main Results:
- The non-antimicrobial soap demonstrated superior removal of Staphylococcus aureus compared to reference soaps (P = .024).
- No significant difference in skin barrier function was observed between the test and reference soaps (P = .736).
Conclusions:
- The non-antimicrobial soap is effective for microbial removal, specifically Staphylococcus aureus.
- The soap exhibits favorable skin compatibility, comparable to established reference products.
- This non-antimicrobial soap presents a safe and effective option for hand hygiene.
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