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Neutrophil-Lymphocyte Ratio Could Be a Marker for Erectile Dysfunction
Ali Aslan1, Yasemin Kaya2, Abdullah Cirakoglu3
1Department of Physiology, School of Medicine, Ordu University, Ordu/Turkey. draslan@yahoo.com.
Urology Journal
|May 9, 2019
Summary
The neutrophil-lymphocyte ratio (NLR), a marker of inflammation, was significantly higher in men with erectile dysfunction (ED). Elevated NLR levels can help predict and diagnose ED.
Area of Science:
- Urology
- Internal Medicine
- Inflammation Research
Background:
- Inflammatory markers are linked to various diseases.
- The neutrophil-lymphocyte ratio (NLR) is a recognized, albeit nonspecific, indicator of inflammation.
Purpose of the Study:
- To investigate the association between erectile dysfunction (ED) and the neutrophil-lymphocyte ratio (NLR).
- To evaluate NLR as a potential diagnostic marker for ED.
Main Methods:
- A study included 90 patients diagnosed with ED and 94 healthy controls.
- Diagnosis of ED was based on the International Index for Erectile Function questionnaire.
- Standard blood tests, including complete blood count and inflammatory markers like NLR, were performed.
Main Results:
- The NLR was significantly higher in the ED group compared to the control group (P < .001).
- Multivariate analysis indicated that NLR (cutoff: 1.574) predicted ED with 81.8% sensitivity and 67.0% specificity.
- Duration of ED (cutoff: 7.5 months) also predicted ED, with 78.8% sensitivity and 63.1% specificity.
Conclusions:
- The neutrophil-lymphocyte ratio (NLR) is elevated in patients with erectile dysfunction.
- NLR demonstrates potential as a predictive and diagnostic biomarker for ED.
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