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Updated: Jan 25, 2026

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
Published on: March 13, 2018
A computational method for the identification of Dengue, Zika and Chikungunya virus species and genotypes
Vagner Fonseca1,2,3, Pieter J K Libin4,5, Kristof Theys5
1Laboratório de Flavivírus, IOC, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Abstract:
In recent years, an increasing number of outbreaks of Dengue, Chikungunya and Zika viruses have been reported in Asia and the Americas. Monitoring virus genotype diversity is crucial to understand the emergence and spread of outbreaks, both aspects that are vital to develop effective prevention and treatment strategies. Hence, we developed an efficient method to classify virus sequences with respect to their species and sub-species (i.e. serotype and/or genotype). This tool provides an easy-to-use software implementation of this new method and was validated on a large dataset assessing the classification performance with respect to whole-genome sequences and partial-genome sequences. Available online: http://krisp.org.za/tools.php.
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