Related Experiment Video
Updated: Jan 25, 2026

Knee Arthrocentesis in Adults
Published on: February 25, 2022
Knee Replacement Bandaging Study (KReBS) evaluating the effect of a two-layer compression bandage system on knee
Liz Cook1, Matthew J Northgraves2, Caroline Fairhurst2
1York Trials Unit, Department of Health Sciences, University of York, Heslington, York, YO10 5DD, UK. liz.cook@york.ac.uk.
Background:
Data from a feasibility study suggest that the use of an inelastic, short-stretch compression bandage following total knee arthroplasty is a safe technique that may improve patient-reported health outcomes, and that it is feasible to recruit to a full-scale study.
Methods:
We will conduct a randomised controlled trial (RCT) of 2600 adult patients, which has 80% power to detect a 1 point difference in the Oxford Knee Score (a patient self-reported assessment of knee pain and function) at 52 weeks. Short stretch compression bandaging will be compared with standard wool and crepe bandaging following total knee arthroplasty. Recruitment will take place in orthopaedic units across the United Kingdom. Secondary outcomes include the EuroQol 5 Dimensions (EQ-5D)-5 L and EQ-5D-3 L scores, pain, length of hospital stay, and complications.
Discussion:
The Knee Replacement Bandaging Study (KReBS) is a large study which aims to contribute to the evidence base for informing clinical decisions for the use of compression bandaging following knee arthroplasty.
Trial Registration:
International Standard Randomised Controlled Trial Register, ISRCTN 87127065 . Registered on 20 February 2017.
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