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Updated: Jan 25, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
[Association between drinking and all-cause mortality in patients with ischemic stroke]
Qianwen Zheng1, Yawen Li1, Lu Zhang1
1Department of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
Alcohol consumption patterns influence mortality risk in ischemic stroke patients. Moderate drinking frequency and duration before stroke, along with continued drinking post-stroke, were linked to lower death rates.
Area of Science:
- Neurology
- Cardiovascular Medicine
- Public Health
Background:
- Ischemic stroke is a leading cause of death and disability worldwide.
- Understanding lifestyle factors, such as alcohol consumption, is crucial for managing post-stroke outcomes.
- Previous research on alcohol and stroke mortality has yielded mixed results.
Purpose of the Study:
- To investigate the association between alcohol drinking patterns and all-cause mortality in patients who have experienced an ischemic stroke.
- To identify specific drinking behaviors that may influence survival rates after ischemic stroke.
Main Methods:
- A cohort of 855 patients with first-episode ischemic stroke was followed for up to 9 years.
- Cox regression models were used to analyze the impact of pre-stroke drinking status, drinking duration, frequency, and post-stroke drinking behavior on mortality.
- Baseline characteristics were compared between drinkers and non-drinkers using the Chi-square test.
Main Results:
- Drinking during the follow-up period was significantly associated with a reduced risk of death (P=0.001).
- Drinking for less than 28 years prior to stroke (P=0.035) and moderate drinking frequency (5-20 times/month for males, 4-9 times/month for females; P=0.030) were linked to lower mortality.
- No significant association was found between pre-stroke drinking status or average single alcohol intake and post-stroke death.
Conclusions:
- Drinking duration and frequency before stroke, as well as drinking status during follow-up, are associated with all-cause mortality in ischemic stroke patients.
- Further research into specific drinking behaviors during the follow-up period is warranted to elucidate the complex relationship between alcohol and post-stroke survival.
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