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Related Experiment Videos

Mannitol-induced acute renal failure.

A Weaver, D A Sica

    Nephron
    |January 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Mannitol, used for glaucoma, can cause kidney failure in patients with existing renal dysfunction. This case highlights the risk of mannitol accumulation leading to acute oliguric renal failure.

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    Area of Science:

    • Nephrology
    • Ophthalmology
    • Pharmacology

    Background:

    • Mannitol is an osmotic diuretic commonly used for acute oliguric renal failure, cerebral edema, and glaucoma.
    • While generally safe, mannitol can accumulate in patients with renal failure, potentially causing adverse effects.
    • Mannitol intoxication symptoms include confusion, lethargy, stupor, and coma.