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Bowel preparation for colonoscopy may decrease the levels of testosterone in Korean men.

Soo-Hyun Lee1, Seung Geon Park1, Moon-Jong Kim1

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Bowel preparation for colonoscopies may lower testosterone levels in men. This effect was more pronounced in younger individuals, suggesting a potential health consideration for routine check-ups.

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Area of Science:

  • Endocrinology
  • Gastroenterology

Background:

  • Colonoscopy is a common medical check-up in Korea.
  • Limited research exists on the health impacts of bowel preparation.

Purpose of the Study:

  • To investigate the influence of bowel preparation on serum testosterone levels in men.
  • To explore age-related differences in this association.

Main Methods:

  • Cross-sectional study involving 1114 men.
  • Comparison of serum total and free testosterone levels between a bowel preparation group and control groups.

Main Results:

  • Significantly lower median total and free testosterone levels were observed in the bowel preparation group.
  • Bowel preparation was independently associated with decreased testosterone levels.
  • The testosterone decline was more pronounced in younger men.

Conclusions:

  • Bowel preparation may independently decrease serum total and free testosterone levels.
  • Age is a significant factor, with younger men experiencing a more substantial decline.